(Sharecast News) - Wall Street stocks were mixed early on Tuesday following big wins for major indices in the previous session.

As of 1530 BST, the Dow Jones Industrial Average was down 0.61% at 40,579.44, while the S&P 500 lost 0.05% to 5,468.32 and the Nasdaq Composite came out the gate 0.21% firmer at 16,919.70.

The Dow opened 250.15 points lower on Tuesday, taking a bite out of gains recorded on Monday.

In focus on Tuesday, on the macro front, the National Federation of Independent Business' small business optimism index decreased to 91.2 in August, the lowest reading in three months, down from 93.7 in July and significantly less than the 93.6 reading expected by economists.

"Historically high inflation remains the top issue for owners as sales expectations plummet and cost pressures increase. Uncertainty among small business owners continues to rise as expectations for future business conditions worsen", said NFIB chief economist Bill Dunkelberg.

The presidential debate between vice president Kamala Harris and former White House resident Donald Trump will also likely draw an amount of investor attention, with the two set to duke it out at 0200 BST.

In the corporate space, cloud computing giant Oracle shares rallied after posting Q1 results that topped expectations on the Street, while Apple traded lower as news that it had lost a €13.0bn EU tax case overshadowed the unveiling of its new iPhone handsets.

Reporting by Iain Gilbert at Sharecast.com

Dow Jones - Risers

Microsoft Corp. (MSFT) $415.60 2.43%

Walmart Inc. (WMT) $78.39 1.35%

McDonald's Corp. (MCD) $295.22 1.35%

3M Co. (MMM) $129.58 0.87%

Unitedhealth Group Inc. (UNH) $598.70 0.77%

Procter & Gamble Co. (PG) $177.20 0.65%

International Business Machines Corporation (CDI) (IBM) $204.37 0.41%

Coca-Cola Co. (KO) $72.10 0.34%

Johnson & Johnson (JNJ) $167.11 0.30%

Walt Disney Co. (DIS) $88.43 0.11%

Dow Jones - Fallers

Goldman Sachs Group Inc. (GS) $468.47 -4.11%

American Express Co. (AXP) $244.49 -2.56%

Boeing Co. (BA) $159.08 -2.35%

Walgreens Boots Alliance, Inc. (WBA) $8.73 -1.96%

Chevron Corp. (CVX) $138.02 -1.62%

JP Morgan Chase & Co. (JPM) $213.40 -1.57%

Nike Inc. (NKE) $78.45 -1.31%

Merck & Co. Inc. (MRK) $114.09 -1.14%

Dow Chemical Co. (DOW) $50.75 -1.07%

Intel Corp. (INTC) $18.89 -0.97%

S&P 500 - Risers

Oracle Corp. (ORCL) $156.98 12.22%

Equinix, Inc. (EQIX) $856.41 2.96%

Broadcom Inc. (AVGO) $144.94 2.93%

Comerica Inc. (CMA) $56.83 2.51%

Microsoft Corp. (MSFT) $415.60 2.43%

AES Corp. (AES) $16.58 2.38%

Amazon.Com Inc. (AMZN) $179.41 2.29%

Gilead Sciences Inc. (GILD) $80.64 1.86%

Digital Realty Trust (DLR) $152.06 1.82%

Johnson Controls International plc (JCI) $69.82 1.78%

S&P 500 - Fallers

Bread Financial Holdings, Inc. (BFH) $48.90 -9.29%

Synchrony Financial (SYF) $44.26 -8.12%

Hewlett Packard Enterprise (HPE) $16.22 -7.87%

Under Armour, Inc. (UA) $6.68 -6.96%

Under Armour Inc. Class A (UAA) $6.99 -6.37%

Ulta Salon, Cosmetics & Fragrance Inc. (ULTA) $357.88 -6.21%

Capital One Financial Corp. (COF) $134.31 -5.81%

Discover Financial Services (DFS) $125.61 -5.79%

Carmax Inc. (KMX) $77.04 -4.45%

Goldman Sachs Group Inc. (GS) $468.47 -4.11%

Nasdaq 100 - Risers

Sirius XM Holdings Inc (SIRI) $25.08 839.33%

Tesla Inc (TSLA) $225.38 4.21%

Broadcom Inc. (AVGO) $144.94 2.93%

Microsoft Corp. (MSFT) $415.60 2.43%

Amazon.Com Inc. (AMZN) $179.41 2.29%

Gilead Sciences Inc. (GILD) $80.64 1.86%

JD.com, Inc. (JD) $26.34 1.76%

Alphabet Inc. Class C (GOOG) $151.27 1.16%

Idexx Laboratories Inc. (IDXX) $485.20 1.01%

Nvidia Corp. (NVDA) $107.51 0.98%

Nasdaq 100 - Fallers

Ulta Salon, Cosmetics & Fragrance Inc. (ULTA) $357.88 -6.21%

Qurate Retail Inc. (QRTEA) $0.48 -3.49%

Paypal Holdings Inc (PYPL) $67.67 -2.42%

American Airlines Group (AAL) $10.98 -2.18%

Marriott International - Class A (MAR) $223.65 -2.16%

Walgreens Boots Alliance, Inc. (WBA) $8.73 -1.96%

Wynn Resorts Ltd. (WYNN) $75.43 -1.92%

Microchip Technology Inc. (MCHP) $73.99 -1.88%

Expedia Group Inc. (EXPE) $130.42 -1.84%

Dollar Tree Inc (DLTR) $66.33 -1.62%