(Sharecast News) - Wall Street stocks turned in a mixed performance on Wednesday as corporate earnings continued to dominate markets.

At the close, the Dow Jones Industrial Average was up 0.44% at 39,056.39, while the S&P 500 was flat at 5,187.67 and the Nasdaq Composite saw out the session 0.318% weaker at 16,302.76.

The Dow closed 172.13 points higher on Wednesday, extending gains recorded in the previous session and giving the blue-chip index a sixth straight winning session.

Earnings were again in focus on Wednesday, with ridesharing giant Lyft and hotel operator Wynn Resorts trading higher on the back of stronger-than-expected quarterly results, while Reddit shares rallied following its first earnings as a public company.

Shopify earnings topped estimates but shares still headed south following weaker-than-expected guidance, Uber revealed it had swung to a quarterly loss despite reporting improved quarterly revenues, Airbnb beat on earnings expectations but issued some weak guidance, and AMC also bested projections thanks to the likes of Dune 2 and Kung Fu Panda 4.

On the macro front, mortgage applications rose by 2.6% in the week ended 3 May, according to the Mortgage Bankers Association of America, recovering from a 2.3% decline in the previous week and snapping a two-week-long streak of sharp declines. Applications for mortgages to purchase a new home rose by 1.8%, while applications to refinance a home jumped by 4.5%

Elsewhere, US wholesale inventories decreased by 0.4% month-on-month in March, matching preliminary estimates and following a downwardly revised 0.2% rise in February. Non-durables stocks saw a decrease of 1.1%, mainly on account of farm products, while inventories of durable goods fell 0.1% in March, according to the Census Bureau.

Reporting by Iain Gilbert at Sharecast.com

Dow Jones - Risers

Amgen Inc. (AMGN) $307.31 2.33%

Boeing Co. (BA) $180.35 2.06%

JP Morgan Chase & Co. (JPM) $195.65 2.03%

Cisco Systems Inc. (CSCO) $47.99 1.51%

International Business Machines Corporation (CDI) (IBM) $169.90 0.90%

3M Co. (MMM) $96.35 0.85%

Goldman Sachs Group Inc. (GS) $447.52 0.71%

American Express Co. (AXP) $236.27 0.67%

Salesforce.Com Inc. (CRM) $278.97 0.65%

Dow Chemical Co. (DOW) $58.65 0.48%

Dow Jones - Fallers

Intel Corp. (INTC) $30.00 -2.22%

Walgreens Boots Alliance, Inc. (WBA) $17.23 -0.69%

Merck & Co. Inc. (MRK) $129.55 -0.64%

Home Depot Inc. (HD) $338.83 -0.55%

Walmart Inc. (WMT) $60.30 -0.53%

Procter & Gamble Co. (PG) $165.07 -0.42%

Nike Inc. (NKE) $93.59 -0.20%

Caterpillar Inc. (CAT) $345.06 -0.14%

Chevron Corp. (CVX) $162.54 -0.08%

Dowdupont Inc. (DWDP) $0.00 0.00%

S&P 500 - Risers

Nektar Therapeutics (NKTR) $1.64 9.12%

Arista Networks Inc. (ANET) $291.67 6.45%

Globe Life Inc. (GL) $89.49 5.08%

Emerson Electric Co. (EMR) $112.81 4.89%

Macerich Co (MAC) $15.84 3.87%

HF Sinclair Corporation (DINO) $57.08 3.83%

HP Inc (HPQ) $29.42 3.63%

NRG Energy Inc. (NRG) $75.82 3.30%

Perrigo Company plc (PRGO) $31.11 3.18%

Norwegian Cruise Line Holdings Ltd (NCLH) $16.09 3.14%

S&P 500 - Fallers

TripAdvisor Inc. (TRIP) $18.16 -28.73%

Brighthouse Financial, Inc. (BHF) $45.78 -10.36%

Broadridge Fin Sol (BR) $190.80 -5.41%

Align Technology Inc. (ALGN) $273.65 -4.49%

Electronic Arts Inc. (EA) $125.24 -3.84%

Paypal Holdings Inc (PYPL) $63.81 -3.20%

Digital Realty Trust (DLR) $140.25 -3.03%

FMC Corp. (FMC) $64.84 -2.86%

Freeport-McMoRan Inc (FCX) $49.96 -2.78%

Equinix, Inc. (EQIX) $692.71 -2.69%

Nasdaq 100 - Risers

Amgen Inc. (AMGN) $307.31 2.33%

Henry Schein Inc. (HSIC) $72.76 2.19%

Vertex Pharmaceuticals Inc. (VRTX) $418.82 2.09%

Charter Communications Inc. (CHTR) $272.78 1.78%

Broadcom Inc. (AVGO) $1,325.37 1.71%

Mercadolibre Inc. (MELI) $1,716.78 1.66%

Booking Holdings Inc. (BKNG) $3,660.00 1.51%

Cisco Systems Inc. (CSCO) $47.99 1.51%

Comcast Corp. (CMCSA) $39.05 1.45%

Starbucks Corp. (SBUX) $73.50 1.38%

Nasdaq 100 - Fallers

Align Technology Inc. (ALGN) $273.65 -4.49%

Electronic Arts Inc. (EA) $125.24 -3.84%

Paypal Holdings Inc (PYPL) $63.81 -3.20%

Liberty Global plc Series C (LBTYK) $17.00 -2.72%

Liberty Global plc Series A (LBTYA) $16.49 -2.48%

Intel Corp. (INTC) $30.00 -2.22%

Intuitive Surgical Inc. (ISRG) $380.51 -2.09%

Illumina Inc. (ILMN) $110.63 -1.94%

Dollar Tree Inc (DLTR) $119.54 -1.75%

Tesla Inc (TSLA) $174.72 -1.74%