Stock Spirits slumped after warning that full-year profits could be €5m-10m below expectations following a "very tough trading period" in the third quarter for the Central European spirits producer.Precious-metal miners such as African Barrick Gold were among the worst performers in the resources sector in afternoon trade as gold prices slumped, along with Egyptian producer Centamin after cutting its forecast for annual production.Insurance firm Esure was also lower after saying that it now expects its full-year combined operating ratio to rise. The company said that it has seen an increase in small bodily injury claims frequency, while premiums for motor insurance continue to fall. Canaccord Genuity climbed thanks to Senior which lifted its rating to 'buy' from 'hold'.FTSE 250 - RisersOcado Group (OCDO) 295.20p +12.46%Howden Joinery Group (HWDN) 368.90p +7.58%Dunelm Group (DNLM) 880.50p +5.26%Cairn Energy (CNE) 150.70p +5.24%Hikma Pharmaceuticals (HIK) 1,963.00p +4.92%Afren (AFR) 73.00p +4.73%Wood Group (John) (WG.) 660.50p +4.43%AO World (AO.) 189.40p +4.35%Synergy Health (SYR) 1,965.00p +4.24%Senior (SNR) 271.00p +4.03%FTSE 250 - FallersStock Spirits Group (STCK) 221.20p -26.36%esure Group (ESUR) 222.80p -6.97%Centamin (DI) (CEY) 48.77p -6.66%Aveva Group (AVV) 1,348.00p -5.73%Wetherspoon (J.D.) (JDW) 798.00p -4.09%NMC Health (NMC) 495.90p -3.62%African Barrick Gold (ABG) 203.90p -3.09%Fisher (James) & Sons (FSJ) 1,239.00p -2.98%Hochschild Mining (HOC) 94.50p -2.58%Restaurant Group (RTN) 654.50p -2.31%