Tests on a drug licensed out by the UK's BTG to Cougar Biotechnology have gone so well the American firm has been told to offer the prostate cancer treatment to study patients who were using a placebo. BTG's shares are up 8%.Hochschild Mining is shining after an encouraging scoping study and an upgrade of reserves for the Inmaculada gold-silver project in southern Peru.Turning to the fallers, JD Wetherspoon lacks fizz. The budget pub group took another swipe at government taxes on the pub industry as it revealed like for like sales grew by just 0.1% in the year ended 25 July, although profit was up over 7%.SThree is also lower. It has joined the growing band of recruiters reporting growing markets, though the Benelux region has yet to move back into growth mode.FTSE 250 - RisersBTG (BGC) 218.00p +8.03%Victrex (VCT) 1,251.00p +5.39%Rightmove (RMV) 742.00p +4.88%Xchanging (XCH) 130.00p +4.00%Redrow (RDW) 135.50p +3.91%Informa (INF) 425.90p +3.52%Telecity Group (TCY) 516.50p +3.30%Hochschild Mining (HOC) 390.60p +3.25%Hargreaves Lansdown (HL.) 412.40p +3.07%Lamprell (LAM) 315.00p +3.01%FTSE 250 - FallersRenishaw (RSW) 951.50p -5.23%JD Wetherspoon (JDW) 425.00p -4.17%RPS Group (RPS) 180.80p -2.69%SThree (STHR) 281.40p -1.95%National Express Group (NEX) 238.80p -1.85%Domino's Pizza UK & IRL (DOM) 458.60p -1.76%Dixons Retail (DXNS) 24.49p -1.65%Great Portland Estates (GPOR) 326.10p -1.57%Paragon Group Of Companies (PAG) 139.80p -1.55%Enterprise Inns (ETI) 89.25p -1.38%